From Paperwork to Patients: The AI Shift in Healthcare

Ambience secures $243M and hits $1.25B valuation as it expands AI that automates care delivery and billing

12 Aug 2025

Artificial intelligence is no longer a future promise in healthcare. It is reshaping the industry today. Ambience, a pioneering AI startup, has raised $243 million to fuel the next phase of its intelligent care platform, now valued at approximately $1.25 billion.

The company’s technology listens to real-time patient visits, generates clinical notes, and suggests billing codes with speed and accuracy. By automating the most burdensome parts of care delivery, Ambience is not just improving workflow. It is redefining how modern medicine operates.

What sets Ambience apart is its full-stack approach. Beyond documentation, it integrates billing, compliance, and revenue optimization, delivering measurable results for both providers and health systems. Already deployed in institutions like Cleveland Clinic and Memorial Hermann, its AI is helping physicians reclaim valuable time and reduce burnout.

Accessibility is also key to its momentum. Ambience is now integrated into Epic’s Toolbox, allowing seamless use within Epic’s Haiku mobile app and other interfaces. This strategic positioning gives hospitals an easy path to adopt the technology without disrupting existing systems.

The funding round was led by Oak HC/FT and Andreessen Horowitz, with participation from the OpenAI Startup Fund, Kleiner Perkins, and Optum Ventures. Their investment reflects growing confidence that AI can solve some of healthcare’s most persistent challenges. With labor shortages, rising costs, and provider fatigue straining the system, intelligent automation is rapidly moving from optional to essential.

While Epic and others race to build in-house AI tools, Ambience is staying ahead by focusing on depth, accuracy, and real-world outcomes. Its expanded platform offers more than transcription. It acts as a digital assistant that actively improves financial and clinical performance.

Challenges around precision, regulation, and adoption still exist. But the greater risk for hospitals may be falling behind. As AI moves from pilot programs to platform-scale implementation, Ambience is positioned at the forefront of a new era where technology empowers care rather than complicates it.

This raise is more than a financial milestone. It is a clear signal that innovation, not incremental change, is driving the future of healthcare.